Infectious Diseases and the Immune System

Inmunovirology Laboratory

2023

Revista Internacional

Interleukin 18 (IL-18) and IL-3 in Extracellular Vesicles: Biomarkers for Durable Elite Control of HIV-1

Poveda E, Fitzgerald W, Reglero C, Pérez-González A, Mariño A, Álvarez H, Valcarce N, Llibre JM, Guillén SM, Muñoz Fernández MA, Ruiz-Mateos E, Margolis L, Lederman MM, Freeman ML.

Vol: 227 Pag: 1381-1385 Revista Internacional

June 15, 2023

J Infect Dis.

Revista Internacional

Toll-like receptor agonists enhance HIV-specific T cell response mediated by plasmacytoid dendritic cells in diverse HIV-1 disease progression phenotypes

Jimenez-Leon MR, Gasca-Capote C, Tarancon-Diez L, Dominguez-Molina B, Lopez-Verdugo M, Ritraj R, Gallego I, Alvarez-Rios AI, Vitalle J, Bachiller S, Camacho-Sojo MI, Perez-Gomez A, Espinosa N, Roca-Oporto C, Rafii-El-Idrissi Benhnia M, Gutierrez-Valencia A, Lopez-Cortes LF, Ruiz-Mateos E.

Vol: 91 Pag: 104549 Revista Internacional

May 1, 2023

EBioMedicine

2022

Revista Internacional

Examining the immune signatures of SARS-CoV-2 infection in pregnancy and the impact on neurodevelopment: Protocol of the SIGNATURE longitudinal study

Garrido-Torres N, Cerrillos L, García Cerro S, Pérez Gómez A, Canal-Rivero M, de Felipe B, Alameda L, Marqués Rodríguez R, Anillo S, Praena J, Duque Sánchez C, Roca C, Paniagua M, López Díaz A, Romero-García R, Olbrich P, Puertas Albarracín MP, Reguera Pozuelo P, Sosa IL, Moreno Dueñas MB, Pineda Cachero R, Zamudio Juan L, García Rumi V, Guerrero Benitez M, Figueroa R, Martín Rendón AM, Partida A, Rodríguez Cocho MI, Gallardo Trujillo C, Gallego Jiménez I, García Spencer S, Gómez Verdugo M, Bermejo Fernández C, Pérez Benito M, Castillo Reina RE, Cejudo López A, Sánchez Tomás C, Chacón Gamero MÁ, Rubio A, Moreno Mellado A, Ramos Herrero V, Starr E, González Fernández de Palacios M, García Victori E, Pavón Delgado A, Fernández Cuervo I, Arias Ruiz A, Menéndez Gil IE, Domínguez Gómez I, Coca Mendoza I, Ayesa-Arriola R, Fañanas L, Leza JC, Cisneros JM, Sánchez Céspedes J, Ruiz-Mateos E, Crespo-Facorro B, Ruiz-Veguilla M

Vol: 10 Pag: 899445 Revista Internacional

Dec. 21, 2022

Front Pediatr.

Revista Internacional

Immune defects associated with lower SARS-CoV-2 BNT162b2 mRNA vaccine response in aged people

Vitallé J, Pérez-Gómez A, Ostos FJ, Gasca-Capote C, Jiménez-León MR, Bachiller S, Rivas-Jeremías I, Silva-Sánchez MDM, Ruiz-Mateos AM, Martín-Sánchez MÁ, López-Cortes LF, Rafii-El-Idrissi Benhnia M, Ruiz-Mateos E.

Vol: 7 Pag: 161045 Revista Internacional

Sept. 8, 2022

JCI Insight.

Revista Internacional

Deciphering the quality of SARS-CoV-2 specific T-cell response associated with disease severity, immune memory and heterologous response

Pérez-Gómez A, Gasca-Capote C, Vitallé J, Ostos FJ, Serna-Gallego A, Trujillo-Rodríguez M, Muñoz-Muela E, Giráldez-Pérez T, Praena-Segovia J, Navarro-Amuedo MD, Paniagua-García M, García-Gutiérrez M, Aguilar-Guisado M, Rivas-Jeremías I, Jiménez-León MR, Bachiller S, Fernández-Villar A, Pérez-González A, Gutiérrez-Valencia A, Rafii-El-Idrissi Benhnia M, Weiskopf D, Sette A, López-Cortés LF, Poveda E, Ruiz-Mateos E; Virgen del Rocío Hospital COVID-19 and COHVID-GS Working Teams

Vol: 12 Pag: 802 Revista Internacional

April 1, 2022

Clin Transl Med.

Revista Internacional

Past and future of HIV infection. A document based on expert opinion

Bouza E, Arribas JR, Alejos B, Bernardino JI, Coiras M, Coll P, Del Romero J, Fuster MJ, Górgolas M, Gutiérrez A, Gracia D, Hernando V, Martínez-Picado J, Martínez Sesmero JM, Martínez E, Moreno S, Mothe B, Navarro ML, Podzamczer D, Pulido F, Ramos JT, Ruiz-Mateos E, Suárez García I, Palomo E.

Vol: 35 Pag: 131-156 Revista Internacional

April 1, 2022

Rev Esp Quimioter

Revista Internacional

Immunoescape of HIV-1 in Env-EL9 CD8 + T cell response restricted by HLA-B*14:02 in a Non progressor who lost twenty-seven years of HIV-1 control

Moyano A, Blanch-Lombarte O, Tarancon-Diez L, Pedreño-Lopez N, Arenas M, Alvaro T, Casado C, Olivares I, Vera M, Rodriguez C, Del Romero J, López-Galíndez C, Ruiz-Mateos E, Prado JG, Pernas M.

Vol: 19 Pag: 6 Revista Internacional

March 26, 2022

Retrovirology

Revista Internacional

Massive Release of CD9+ Microvesicles in Human Immunodeficiency Virus Infection, Regardless of Virologic Control

Poveda E, Tabernilla A, Fitzgerald W, Salgado-Barreira Á, Grandal M, Pérez A, Mariño A, Álvarez H, Valcarce N, González-García J, Bernardino JI, Gutierrez F, Fujioka H, Crespo M, Ruiz-Mateos E, Margolis L, Lederman MM, Freeman ML.

Vol: 225 Pag: 1040-1049 Revista Internacional

March 15, 2022

J Infect Dis.

2021

Revista Internacional

Signatures of immune selection in intact and defective proviruses distinguish HIV-1 elite controllers

Lian X, Gao C, Sun X, Jiang C, Einkauf KB, Seiger KW, Chevalier JM, Yuki Y, Martin M, Hoh R, Peluso MJ, Carrington M, Ruiz-Mateos E, Deeks SG, Rosenberg ES, Walker BD, Lichterfeld M, Yu XG.

Vol: 13 Pag: 4097 Revista Internacional

Dec. 15, 2021

Sci Transl Med.

Revista Internacional

Elevated Anti-SARS-CoV-2 Antibodies and IL-6, IL-8, MIP-1β, Early Predictors of Severe COVID-19. Microorganisms

Codina H, Vieitez I, Gutierrez-Valencia A, Skouridou V, Martínez C, Patiño L, Botero-Gallego M, Trujillo-Rodríguez M, Serna-Gallego A, Muñoz-Muela E, Bobillo MM, Pérez A, Cabrera-Alvar JJ, Crespo M, O'Sullivan CK, Ruiz-Mateos E, Poveda E.

Vol: 9 Pag: 2259 Revista Internacional

Oct. 29, 2021

Microorganisms

Revista Internacional

Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection

Pérez-Gómez A, Vitallé J, Gasca-Capote C, Gutierrez-Valencia A, Trujillo-Rodriguez M, Serna-Gallego A, Muñoz-Muela E, Jiménez-Leon MLR, Rafii-El-Idrissi Benhnia M, Rivas-Jeremias I, Sotomayor C, Roca-Oporto C, Espinosa N, Infante-Domínguez C, Crespo-Rivas JC, Fernández-Villar A, Pérez-González A, López-Cortés LF, Poveda E, Ruiz-Mateos E; Virgen del Rocío Hospital COVID-19 Working Team

Vol: 18 Pag: 2128-2139 Revista Internacional

Sept. 1, 2021

Cell Mol Immunol.

Revista Internacional

Differential miRNA plasma profiles associated with the spontaneous loss of HIV-1 control: miR-199a-3p and its potential role as a biomarker for quick screening of elite controllers

Masip J, Gasca-Capote C, Jimenez-Leon MR, Peraire J, Perez-Gomez A, Alba V, Malo AI, Leal L, Martín CR, Rallón N, Viladés C, Olona M, Vidal F, Ruiz-Mateos E, Rull A;

Vol: 11 Pag: 474 Revista Internacional

July 1, 2021

Clin Transl Med.

Revista Internacional

The Other Side of SARS-CoV-2 Infection: Neurological Sequelae in Patients

Alonso-Bellido IM, Bachiller S, Vázquez G, Cruz-Hernández L, Martínez E, Ruiz-Mateos E, Deierborg T, Venero JL, Real LM, Ruiz R.

Vol: 13 Pag: 632-673 Revista Internacional

April 6, 2021

Front Aging Neurosci.

2020

Revista Internacional

Persistent HIV-controllers are more prone to spontaneously clear HCV: a retrospective cohort study

Dominguez-Molina B, Tarancon-Diez L, Milanés-Guisado Y, Genebat M, Resino S, Rodriguez C, Gonzalez-García J, Rallón N, Pernas M, Casado C, Lopez-Galíndez C, León A, Benito JM, García F, Del Romero J, Viciana P, Lopez-Cortes LF, Leal M, Ruiz-Mateos E

Vol: 23 Revista Internacional

Sept. 1, 2020

J Int AIDS Soc.

Revista Internacional

Modulation of Monocyte Activation and Function during Direct Antiviral Agent Treatment in Patients Coinfected with HIV and Hepatitis C Virus

De Pablo-Bernal RS, Jimenez-Leon MR, Tarancon-Diez L, Gutierrez-Valencia A, Serna-Gallego A, Trujillo-Rodriguez M, Alvarez-Rios AI, Milanes-Guisado Y, Espinosa N, Roca-Oporto C, Viciana P, Lopez-Cortes LF, Ruiz-Mateos E.

Vol: 64 Revista Internacional

Aug. 20, 2020

Antimicrob Agents Chemother

Revista Internacional

PLA2G1B is involved in CD4 anergy and CD4 lymphopenia in HIV-infected patients

Pothlichet J, Rose T, Bugault F, Jeammet L, Meola A, Haouz A, Saul F, Geny D, Alcami J, Ruiz-Mateos E, Teyton L, Lambeau G, Thèze J.

Vol: 130 Pag: 2872-2887 Revista Internacional

June 1, 2020

J Clin Invest.

Revista Internacional

Antiretroviral Treatment for HIV Elite Controllers?

Ruiz-Mateos E, Poveda E, Lederman MM.

Vol: 19 Pag: 121-133 Revista Internacional

May 19, 2020

Pathog Immun.

Revista Internacional

Immunological history governs human stem cell memory CD4 heterogeneity via the Wnt signaling pathway

Kared H, Tan SW, Lau MC, Chevrier M, Tan C, How W, Wong G, Strickland M, Malleret B, Amoah A, Pilipow K, Zanon V, Govern NM, Lum J, Chen JM, Lee B, Florian MC, Geiger H, Ginhoux F, Ruiz-Mateos E, Fulop T, Rajasuriar R, Kamarulzaman A, Ng TP, Lugli E, Larbi A.

Vol: 11 Pag: 821 Revista Internacional

Feb. 10, 2020

Nat Commun.

Revista Internacional

Permanent control of HIV-1 pathogenesis in exceptional elite controllers: a model of spontaneous cure

Casado C, Galvez C, Pernas M, Tarancon-Diez L, Rodriguez C, Sanchez-Merino V, Vera M, Olivares I, De Pablo-Bernal R, Merino-Mansilla A, Del Romero J, Lorenzo-Redondo R, Ruiz-Mateos E, Salgado M, Martinez-Picado J, Lopez-Galindez C.

Vol: 10 Pag: 1902 Revista Internacional

Feb. 5, 2020

Sci Rep.

Principal Investigator

Ezequiel Ruiz-Mateos Carmona

ORCID CV

Infectious Diseases and the Immune System

Inmunovirology Laboratory

Revista Internacional

Revista Internacional

Revista Internacional

Revista Internacional

Revista Internacional

Revista Internacional

Revista Internacional

Revista Internacional

Revista Internacional

Revista Internacional

Revista Internacional

Revista Internacional

Revista Internacional

Revista Internacional

Revista Internacional

Revista Internacional

Revista Internacional

Revista Internacional

Revista Internacional

Infectious Diseases and the Immune System

Neurosciences

Oncohematology and Genetics

Cardiovascular and Respiratory Pathology/Other Systemic Diseases

Liver, Digestive and Inflammatory Diseases

Animal Production and Experimentation

Bioinformatics and Computational Biology

Flow cytometry service

Cell and Tissue Culture

Sterilization, Cleaning and Cryobiology

Scientific Instrumentation Service IBiS

Genomics and Sequencing

Histology

Computer Aided Design and 3D Printing

Optical and Confocal Microscopy

Proteomic

Radioactivity

Biomedical Research Support Service (SAIBIS)

iPSC and Organoids

IBiS Spaces