Dinámica del Genoma en Cáncer

MDC1 maintains active elongation complexes of RNA Polymerase II

CtIP-dependent nascent RNA expression flanking DNA breaks guides the choice of DNA repair pathway

Evolving Landscape of DNA Repair in Cancer Therapy Biomedicines

Methylation of the central transcriptional regulator KLF4 by PRMT5 is required for DNA end resection and recombination

CtIP-Specific Roles during Cell Reprogramming Have Long-Term Consequences in the Survival and Fitness of Induced Pluripotent Stem Cells

A genome-wide screening uncovers the role of CCAR2 as an antagonist of DNA end resection Nature Communications

Neddylation inhibits CtIP-mediated resection and regulates DNA double strand break repair pathway choice

New tools to study DNA double-strand break repair pathway choice

DGCR8-mediated disruption of miRNA biogenesis induces cellular senescence in primary fibroblasts

Regulation of the microRNA processor DGCR8 by the tumor suppressor ING1