Oncohematología y Genética

Patología molecular de los sarcomas y otros tumores

2024
2023
Revista Internacional

VE-Cadherin modulates β-catenin/TCF-4 to enhance Vasculogenic Mimicry

Daniel Delgado-Bellido , Esteban Zamudio-Martínez , Mónica Fernández-Cortés , Ana Belén Herrera-Campos , Joaquin Olmedo-Pelayo , Carmen Jordán Perez , José Expósito , Enrique de Álava , Ana Teresa Amaral , Francisco O' Valle , Angel Garcia Diaz , F J Oliver

Revista Internacional
2022
Revista Internacional

Endoglin and MMP14 Contribute to Ewing Sarcoma Spreading by Modulation of Cell-Matrix Interactions

Pilar Puerto-Camacho, Juan Díaz-Martín, Joaquín Olmedo-Pelayo, Alfonso Bolado-Carrancio, Carmen Salguero-Aranda, Carmen Jordán-Pérez, Marina Esteban-Medina, Inmaculada Álamo-Álvarez, Daniel Delgado-Bellido, Laura Lobo-Selma, Joaquín Dopazo, Ana Sastre, Javier Alonso, Thomas G P Grünewald, Carmelo Bernabeu, Adam Byron, Valerie G Brunton, Ana Teresa Amaral, Enrique de Álava

Revista Internacional
2021
Revista Internacional

Selective inhibition of HDAC6 regulates expression of the oncogenic driver EWSR1-FLI1 through the EWSR1 promoter in Ewing sarcoma

Daniel J García-Domínguez, Nabil Hajji, Sara Sánchez-Molina, Elisabet Figuerola-Bou, Rocío M de Pablos, Ana M Espinosa-Oliva, Eduardo Andrés-León, Laura Carmen Terrón-Camero, Rocío Flores-Campos, Guillem Pascual-Pasto, María José Robles, Isidro Machado, Antonio Llombart-Bosch, Giovanna Magagnoli, Katia Scotlandi, Ángel M Carcaboso, Jaume Mora, Enrique de Álava, Lourdes Hontecillas-Prieto

Revista Internacional
2020
Revista Internacional

An inducible ectopic expression system of EWSR1-FLI1 as a tool for understanding Ewing sarcoma oncogenesis

Garcia-Dominguez, DJ; Hontecillas-Prieto, L; Leon, EA; Sanchez-Molina, S; Rodriguez-Nunez, P; Moron, FJ; Hajji, N; Mackintosh, C; de Alava, E

Vol: PLOS ONE Revista Internacional
Revista Internacional

Biopsia liquida en oncologia: Consenso de la Sociedad Espanola de Oncologia Medica (SEOM) y la Sociedad Espanola de Anatomia Patologica (SEAP)

Alvarez-Alegret R; Rojo Todo F; Garrido P; Bellosillo B; Rodriguez-Lescure A; Rodriguez-Peralto JL; Vera R; de Alava E; Garcia-Campelo R; Remon J

Vol: Revista espanola de patologia Revista Internacional
Revista Internacional

Both Epimutations and Chromosome Aberrations Affect Multiple Imprinted Loci in Aggressive Wilms Tumors

Pignata, L; Palumbo, O; Cerrato, F; Acurzio, B; de Alava, E; Roma, J; Gallego, S; Mora, J; Carella, M; Riccio, A; Verde, G

Vol: CANCERS Revista Internacional
Revista Internacional

Breakthrough Technologies Reshape the Ewing Sarcoma Molecular Landscape

Salguero-Aranda, C; Amaral, AT; Olmedo-Pelayo, J; Diaz-Martin, J; de Alava, E

Vol: CELLS Revista Internacional
Revista Internacional

Breast tumor cells promotes the horizontal propagation of EMT, stemness, and metastasis by transferring the MAP17 protein between subsets of neoplastic cells

Garcia-Heredia, JM; Otero-Albiol, D; Perez, M; Perez-Castejon, E; Munoz-Galvan, S; Carnero, A

Vol: ONCOGENESIS Revista Internacional
Revista Internacional

COVID-19 Gastrointestinal Manifestations Are Independent Predictors of PICU Admission in Hospitalized Pediatric Patients

Jimenez, DG; Rodriguez-Belvis, MV; Gonzalez, PF; Ortega, GD; Segarra, O; Benitez, EM; Tirado, DG; Romero, RG; Lopez, RV; Crehua-Gaudiza, E; Queralt, M; Perez, LMP; Martin, JJD

Vol: PEDIATRIC INFECTIOUS DISEASE JOURNAL Revista Internacional
Revista Internacional

COVID-19 outbreaks in a transmission control scenario: challenges posed by social and leisure activities, and for workers in vulnerable conditions, Spain, early summer 2020

Herrador, BRG; Ariza, SR; Zamalloa, PL; Valbuena, AC; Paches, PJ; Monge, S; San Miguel, LG; Olaso, OP; Sagrado, TS; Castaneda, MP; Rodriguez, BS; Moros, MJS; Soria, FS; Gomez, MG; Martinez, CV; Sanz, CD; Dos Santos, RA; Lorusso, N; Ubago, AC; Pla, ED; Jimenez, CF; Vazquez, MG; Gracia, ADC; Boone, ALD; Ibanez, AF; Fernandez, BA; Duran, JG; Rovira, MC; Castell, MS; Moreno, MLR; Frances, AP; Raymundo, LV; Curiel-Olmo, S; Cuesta, MG; Jane, M; Martinez, A; Izquierdo, C; Perez, AIR; Marin, VR; Corrales, IL; Saavedra, RR; Perez, MJR; Hernandez, SG; Lopez, MG; Rodriguez, MDM; Sopena, CR; Arevalo, OLR; Guillem, SB; Cuevas, AT; Torvisco, MDLT; Salete, CA; Gonzalez, BM; Villar, AIG; Martinez, OP; Castillo, IL; Garduno, IR; Diaz, JS; Bueno, SJ; Perez, DC; Castro, LFH; Anes, AAG; Garcia-Fulgueiras, A; Chirlaque, MD; Barranco, MI; Cenoz, MG; Sayon-Orea, C; Casado, I; Amores, MO; Carollo, OM; Perez, ACI; Ochoa, EM; Zarate, MPM

Vol: EUROSURVEILLANCE Revista Internacional
Revista Internacional

Canonical non-homologous end-joining promotes genome mutagenesis and translocations induced by transcription-associated DNA topoisomerase 2 activity

Olmedo-Pelayo, J; Rubio-Contreras, D; Gomez-Herreros, F

Vol: NUCLEIC ACIDS RESEARCH Revista Internacional
Revista Internacional

Clinical Factors Associated With Overuse of Asthma Reliever Medication

Urrutia, I; Delgado, J; Dominguez-Ortega, J; Mascaros, E; Perez, M; Resler, G; Plaza, V; Flor, X; Vega, JM; Martinez, GL; Fernandez, JP; Munoz, X; Roger, A; Navarro, EM; Gomez, E; Adrados, ACG; Perez, RG; Perez, JMH; Barcala, FJG; Rey, JG; Bobolea, ID; Garcia, SS; Saenz, JTG; Cebollera, P; Vina, AL; Moragon, EM; Valero, A; Campos, RD; Talavera, IG; Viteri, SA; Robaina, JCG; Arrondo, AP

Vol: JOURNAL OF INVESTIGATIONAL ALLERGOLOGY AND CLINICAL IMMUNOLOGY Revista Internacional
Revista Internacional

Clinical performance evaluation of the Idylla (TM) EGFR Mutation Test on formalin-fixed paraffin-embedded tissue of non-small cell lung cancer

Delgado-Garcia, M; Weynand, B; Gomez-Izquierdo, L; Hernandez, MJ; Blanco, AM; Varela, M; Matias-Guiu, X; Nadal, E; Marquez-Lobo, B; Alarcao, A; de Alava, E; Biscuola, M

Vol: BMC CANCER Revista Internacional
Revista Internacional

Downregulation of MYPT1 increases tumor resistance in ovarian cancer by targeting the Hippo pathway and increasing the stemness

Munoz-Galvan, S; Felipe-Abrio, B; Verdugo-Sivianes, EM; Perez, M; Jimenez-Garcia, MP; Suarez-Martinez, E; Estevez-Garcia, P; Carnero, A

Vol: MOLECULAR CANCER Revista Internacional
Revista Internacional

Effectiveness of the combination elvitegravir/cobicistat/tenofovir/emtricitabine (EVG/COB/TFV/FTC) plus darunavir among treatment-experienced patients in clinical practice: a multicentre cohort study

Suarez-Garcia, I; Moreno, C; Ruiz-Alguero, M; Perez-Elias, MJ; Navarro, M; Martinez, MD; Viciana, P; Perez-Martinez, L; Gorgolas, M; Amador, C; de Zarraga, MA; Jarrin, I

Vol: AIDS RESEARCH AND THERAPY Revista Internacional
Revista Internacional

Efficacy and safety of a comprehensive educational antimicrobial stewardship program focused on antifungal use

Martin-Gutierrez, G; Penalva, G; de Pipaon, MRP; Aguilar, M; Gil-Navarro, MV; Perez-Blanco, JL; Perez-Moreno, MA; Amaya-Villar, R; Ferraadiz-Millon, C; Gascon, ML; Goycochea-Valdivia, WA; Jimenez-Mejias, ME; Navarro, MD; Lepe, JA; Alvarez-Marin, R; Neth, O; Guisado-Gil, AB; Infante-Dominguez, C; Molina, J; Cisneros, JM

Vol: JOURNAL OF INFECTION Revista Internacional
Revista Internacional

Haploidentical transplantation in high-risk pediatric leukemia: A retrospective comparative analysis on behalf of the Spanish working Group for bone marrow transplantation in children (GETMON) and the Spanish Grupo for hematopoietic transplantation (GETH)

Perez-Martinez, A; Ferreras, C; Pascual, A; Gonzalez-Vicent, M; Alonso, L; Badell, I; Navarro, JMF; Regueiro, A; Plaza, M; Hurtado, JMP; Benito, A; Belendez, C; Couselo, JM; Fuster, JL; Diaz-Almiron, M; Bueno, D; Mozo, Y; Marsal, J; Lopez, AG; Sisinni, L; de Heredia, CD; Diaz, MA

Vol: AMERICAN JOURNAL OF HEMATOLOGY Revista Internacional
Revista Internacional

Haploidentical transplantation in pediatric non-malignant diseases: A retrospective analysis on behalf of the Spanish Group for Hematopoietic Transplantation (GETH)

Canizales, JT; Ferreras, C; Pascual, A; Alonso, L; Regueiro, A; Plaza, M; Hurtado, JMP; Benito, A; Couselo, JM; Fuster, JL; Diaz-Almiron, M; Bueno, D; Mozo, Y; Lopez, AG; Vicario, JL; Balas, A; Sisinni, L; de Heredia, CD; Perez-Martinez, A

Vol: EUROPEAN JOURNAL OF HAEMATOLOGY Revista Internacional
Revista Internacional

Hippo pathway effectors YAP1/TAZ induce an EWS-FLI1-opposing gene signature and associate with disease progression in Ewing sarcoma

Rodriguez-Nunez, P; Romero-Perez, L; Amaral, AT; Puerto-Camacho, P; Jordan, C; Marcilla, D; Grunewald, TGP; Alonso, J; de Alava, E; Diaz-Martin, J

Vol: JOURNAL OF PATHOLOGY Revista Internacional
Revista Internacional

Implications of maraviroc and/or rapamycin in a mouse model of fragility

Perez-Martinez, L; Romero, L; Munoz-Galvan, S; Verdugo-Sivianes, EM; Rubio-Mediavilla, S; Oteo, JA; Carnero, A; Blanco, JR

Vol: AGING-US Revista Internacional
Revista Internacional

LOXL2 promotes oncogenic progression in alveolar rhabdomyosarcoma independently of its catalytic activity

Almacellas-Rabaiget, O; Monaco, P; Huertas-Martinez, J; Garcia-Monclus, S; Chicon-Bosch, M; Maqueda-Marcos, S; Fabra-Heredia, I; Herrero-Martin, D; Rello-Varona, S; de Alava, E; Lopez-Alemany, R; Giangrande, PH; Tirado, OM

Vol: CANCER LETTERS Revista Internacional
Revista Internacional

Liquid biopsy in oncology: a consensus statement of the Spanish Society of Pathology and the Spanish Society of Medical Oncology

Remon, J; Garcia-Campelo, R; de Alava, E; Vera, R; Rodriguez-Peralto, JL; Rodriguez-Lescure, A; Bellosillo, B; Garrido, P; Rojo, F; Alvarez-Alegret, R

Vol: CLINICAL & TRANSLATIONAL ONCOLOGY Revista Internacional
Revista Internacional

Low Prevalence of HER2-Positive Breast Carcinomas among Screening Detected Breast Cancers

Lopez-Garcia, MA; Carretero-Barrio, I; Perez-Mies, B; Chiva, M; Castilla, C; Vieites, B; Palacios, J

Vol: CANCERS Revista Internacional
Revista Internacional

Multi-center real-world comparison of the fully automated Idylla (TM) microsatellite instability assay with routine molecular methods and immunohistochemistry on formalin-fixed paraffin-embedded tissue of colorectal cancer

Velasco, A; Tokat, F; Bonde, J; Trim, N; Bauer, E; Meeney, A; de Leng, W; Chong, G; Dalstein, V; Kis, LL; Lorentzen, JA; Tomic, S; Thwaites, K; Putzova, M; Birnbaum, A; Qazi, R; Primmer, V; Dockhorn-Dworniczak, B; Hernandez-Losa, J; Soares, FA; Gertler, AA; Kalman, M; Wong, C; Carraro, DM; Sousa, AC; Reis, RM; Fox, SB; Fassan, M; Brevet, M; Merkelbach-Bruse, S; Colling, R; Soilleux, E; Teo, RYW; D'Haene, N; Nolet, S; Ristimaki, A; Vaisanen, T; Chapusot, C; Soruri, A; Unger, T; Wecgowiec, J; Biscuola, M; Frattini, M; Long, AN; Campregher, PV; Matias-Guiu, X

Vol: VIRCHOWS ARCHIV Revista Internacional
Revista Internacional

Nivolumab and sunitinib combination in advanced soft tissue sarcomas: a multicenter, single-arm, phase Ib/II trial

Martin-Broto, J; Hindi, N; Grignani, G; Martinez-Trufero, J; Redondo, A; Valverde, C; Stacchiotti, S; Lopez-Pousa, A; D'Ambrosio, L; Gutierrez, A; Perez-Vega, H; Encinas-Tobajas, V; de Alava, E; Collini, P; Pena-Chilet, M; Dopazo, J; Carrasco-Garcia, I; Lopez-Alvarez, M; Moura, DS; Lopez-Martin, JA

Vol: JOURNAL FOR IMMUNOTHERAPY OF CANCER Revista Internacional
Revista Internacional

Outcomes of the PIRASOA programme, an antimicrobial stewardship programme implemented in hospitals of the Public Health System of Andalusia, Spain: an ecologic study of time-trend analysis

Rodriguez-Bano, J; Perez-Moreno, MA; Penalva, G; Garnacho-Montero, J; Pinto, C; Salcedo, I; Fernandez-Urrusuno, R; Neth, O; Gil-Navarro, MV; Perez-Milena, A; Sierra, R; Estella, A; Lupion, C; Irastorza, A; Marquez, JL; Pascual, A; Rojo-Martin, MD; Perez-Lozano, MJ; Valencia-Martin, R; Cisneros, JM

Vol: CLINICAL MICROBIOLOGY AND INFECTION Revista Internacional
Revista Internacional

Pazopanib for treatment of typical solitary fibrous tumours: a multicentre, single-arm, phase 2 trial

Martin-Broto, J; Cruz, J; Penel, N; Le Cesne, A; Hindi, N; Luna, P; Moura, DS; Bernabeu, D; de Alava, E; Lopez-Guerrero, JA; Dopazo, J; Pena-Chilet, M; Gutierrez, A; Collini, P; Karanian, M; Redondo, A; Lopez-Pousa, A; Grignani, G; Diaz-Martin, J; Marcilla, D; Fernandez-Serra, A; Gonzalez-Aguilera, C; Casali, PG; Blay, JY; Stacchiotti, S

Vol: LANCET ONCOLOGY Revista Internacional
Revista Internacional

Pembrolizumab as Consolidation Strategy in Patients with Multiple Myeloma: Results of the GEM-Pembresid Clinical Trial

Puig, N; Corchete-Sanchez, LA; Perez-Moran, JJ; Davila, J; Paino, T; de la Rubia, J; Oriol, A; Martin-Sanchez, J; de Arriba, F; Blad, J; Blanchard, MJ; Gonzalez-Calle, V; Garcia-Sanz, R; Paiva, B; Lahuerta, JJ; San-Miguel, JF; Mateos, MV; Ocio, EM

Vol: CANCERS Revista Internacional
Revista Internacional

Phase III Trial of Adjuvant Capecitabine After Standard Neo-/Adjuvant Chemotherapy in Patients With Early Triple-Negative Breast Cancer (GEICAM/2003-11_CIBOMA/2004-01)

Lluch, A; Barrios, CH; Torrecillas, L; Ruiz-Borrego, M; Bines, J; Segalla, J; Guerrero-Zotano, A; Garcia-Saenz, JA; Torres, R; de la Haba, J; Garcia-Martinez, E; Gomez, HL; Llombart, A; Bofill, JS; Baena-Canada, JM; Barnadas, A; Calvo, L; Perez-Michel, L; Ramos, M; Fernandez, I; Rodriguez-Lescure, A; Cardenas, J; Vinholes, J; de Duenas, EM; Godes, MJ; Segui, MA; Anton, A; Lopez-Alvarez, P; Moncayo, J; Amorim, G; Villar, E; Reyes, S; Sampaio, C; Cardemil, B; Escudero, MJ; Bezares, S; Carrasco, E; Martin, M; Corona, J; Jara, C; Cardemil, B; Toro, R; Pimentel, C; Hernando, B; Vicente, E; Zagame, L; Gil, M; Estevez, LG; Rodriguez, C; de la Cruz, MA; Tello, JM; Campos, S; Lomas, M; Capdevile, D; Campos, M; Margeli, M; Andres, R; Tusquets, I; Ballesteros, A; Guerrero, A; Arguello, M; Rodriguez, JL; Munoz, M; Florian, J; Azevedo, S; Mondragon, R; Peralta, J; Palomo, AE; Barajas, LJ; Arcusa, A; Carranza, H; Garcia, C; Umbria, C; Ales, JE; Vega, JML; Romeo, M; Valero, J; Alonso, JL; Mathias, C; Gutierrez, F; Adrover, E; Nunez, P; Mendiola, C; Cassinello, J; de la Huerta, A

Vol: JOURNAL OF CLINICAL ONCOLOGY Revista Internacional
Revista Internacional

Post-Translational Modifications of Cytochrome c in Cell Life and Disease

Guerra-Castellano, A; Marquez, I; Perez-Mejias, G; Diaz-Quintana, A; De la Rosa, MA; Diaz-Moreno, I

Vol: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Revista Internacional
Revista Internacional

Prognostic value of the TGF beta 1 rs4803455 single nucleotide polymorphism in small cell lung cancer

de Miguel, PA; Enguix-Riego, MV; Cacicedo, J; Delgado, BD; Perez, M; Praena-Fernandez, JM; Cortes, LQ; Garcia, PB; del Campo, ER; Guerra, JLL

Vol: TUMORI J Revista Internacional
Revista Internacional

RING1B recruits EWSR1-FLI1 and cooperates in the remodeling of chromatin necessary for Ewing sarcoma tumorigenesis

Sanchez-Molina, S; Figuerola-Bou, E; Blanco, E; Sanchez-Jimenez, M; Taboas, P; Gomez, S; Ballare, C; Garcia-Dominguez, DJ; Prada, E; Hontecillas-Prieto, L; Carcaboso, AM; Tirado, OM; Hernandez-Munoz, I; de Alava, E; Lavarino, C; Di Croce, L; Mora, J

Vol: SCIENCE ADVANCES Revista Internacional
Revista Internacional

Ruxolitinib in refractory acute and chronic graft-versus-host disease: a multicenter survey study

Gomez, VE; Garcia-Gutierrez, V; Corral, LL; Cadenas, IG; Martinez, AP; Malaver, FMJ; Caballero-Velazquez, T; Sierra, PGA; Alegria, MCV; Salinas, IPM; Cabrera, CC; Vicent, MG; Torres, NR; Porras, RP; Coll, CF; Orti, G; Ferreiras, DV; Llanza, RD; Moles, P; Velazquez-Kennedy, K; Mende, MJ; Barrigon, DC; Perez, E; Bofarull, RM; Gerosa, SS; Sierra, J; Poch, M; Ripa, MTZ; Perez, MDA; Angulo, BM; Ortega, IS; Caballer, JS; Gomez, JM; Tocino, IE; Perez-Simon, JA

Vol: BONE MARROW TRANSPLANTATION Revista Internacional
Revista Internacional

Sarcoma European and Latin American Network (SELNET) Recommendations on Prioritization in Sarcoma Care During the COVID-19 Pandemic

Martin-Broto, J; Hindi, N; Aguiar, S; Badilla-Gonzalez, R; Castro-Oliden, V; Chacon, M; Correa-Generoso, R; de Alava, E; Donati, DM; Eriksson, M; Falla-Jimenez, M; German, G; Silva, MLG; Gouin, F; Gronchi, A; Haro-Varas, JC; Jimenez-Brenes, N; Kasper, B; de Mello, CAL; Maki, R; Martinez-Delgado, P; Martinez-Said, H; Martinez-Tlahuel, JL; Morales-Perez, JM; Munoz-Casares, FC; Nakagawa, SA; Ortiz-Cruz, EJ; Palmerini, E; Patel, S; Moura, DS; Stacchiotti, S; Sunyach, MP; Valverde, CM; Waisberg, F; Blay, JY

Vol: ONCOLOGIST Revista Internacional
Revista Internacional

Sarcoma stratification by combined pH2AX and MAP17 (PDZK1IP1) levels for a better outcome on doxorubicin plus olaparib treatment

Perez, M; Garcia-Heredia, JM; Felipe-Abrio, B; Munoz-Galvan, S; Martin-Broto, J; Carnero, A

Vol: SIGNAL TRANSDUCTION AND TARGETED THERAPY Revista Internacional
Revista Internacional

Synergistic Enhancement of Cancer Therapy Using HDAC Inhibitors: Opportunity for Clinical Trials

Hontecillas-Prieto, L; Flores-Campos, R; Silver, A; de Alava, E; Hajji, N; Garcia-Dominguez, DJ

Vol: FRONTIERS IN GENETICS Revista Internacional
Revista Internacional

The Frequency and Prognostic Significance of the Histologic Type in Early-stage Ovarian Carcinoma A Reclassification Study by the Spanish Group for Ovarian Cancer Research (GEICO)

Leskela, S; Romero, I; Cristobal, E; Perez-Mies, B; Rosa-Rosa, JM; Gutierrez-Pecharroman, A; Santon, A; Gonzalez, BO; Lopez-Reig, R; Hardisson, D; Vera-Sempere, F; Illueca, C; Vieites, B; Lopez-Guerrero, JA; Palacios, J; Poveda, A

Vol: AMERICAN JOURNAL OF SURGICAL PATHOLOGY Revista Internacional
Revista Internacional

Treatment-driven selection of chemoresistant Ewing sarcoma tumors with limited drug distribution

Castillo-Ecija, H; Monterrubio, C; Pascual-Pasto, G; Gomez-Gonzalez, S; Garcia-Dominguez, DJ; Hontecillas-Prieto, L; Resa-Pares, C; Burgueno, V; Paco, S; Olaciregui, NG; Vila-Ubach, M; Restrepo-Perdomo, C; Cuadrado-Vilanova, M; Balaguer-Lluna, L; Perez-Jaume, S; Castaneda, A; Santa-Maria, V; Roldan, M; Sunol, M; de Alava, E; Mora, J; Lavarino, C; Carcaboso, AM

Vol: JOURNAL OF CONTROLLED RELEASE Revista Internacional
Revista Internacional

Unraveling the Influence of Common von Willebrand factor variants on von Willebrand Disease Phenotype: An Exploratory Study on the Molecular and Clinical Profile of von Willebrand Disease in Spain Cohort

Borras, N; Garcia-Martinez, I; Batlle, J; Perez-Rodriguez, A; Parra, R; Altisent, C; Lopez-Fernandez, MF; Pinto, JC; Batlle-Lopez, F; Cid, AR; Bonanad, S; Cabrera, N; Moret, A; Mingot-Castellano, ME; Navarro, N; Perez-Montes, R; Marcellini, S; Moreto, A; Herrero, S; Soto, I; Fernandez-Mosteirin, N; Jimenez-Yuste, V; Alonso, N; de Andres-Jacob, A; Fontanes, E; Campos, R; Paloma, MJ; Bermejo, N; Berrueco, R; Mateo, J; Arribalzaga, K; Marco, P; Palomo, A; Quismondo, NC; Inigo, B; Nieto, MD; Vidal, R; Martinez, MP; Aguinaco, R; Tenorio, M; Ferreiro, M; Garcia-Frade, J; Rodriguez-Huerta, AM; Cuesta, J; Rodriguez-Gonzalez, R; Garcia-Candel, F; Dobon, M; Aguilar, C; Corrales, I; Vidal, F

Vol: THROMBOSIS AND HAEMOSTASIS Revista Internacional
2019
Revista Internacional

Clinical challenges and implications of intratumor heterogeneity.

Palacios J, Matías-Guiu X, Rodríguez-Peralto JL, de Álava E, López JI

Vol: Rev Esp Patol. Revista Internacional
Revista Internacional

Computer-Assisted Definition of the Inflammatory Infiltrates in Patients With Different Categories of Banff Kidney Allograft Rejection.

Aguado-Domínguez E, Cabrera-Pérez R, Suarez-Benjumea A, Abad-Molina C, Núñez-Roldán A, Aguilera I

Vol: Front Immunol Revista Internacional
Revista Internacional

DNA methylation profiling distinguishes Ewing-like sarcoma with EWSR1-NFATc2 fusion from Ewing sarcoma.

Koelsche C, Kriegsmann M, Kommoss FKF, Stichel D, Kriegsmann K, Vokuhl C, Grünewald TGP, Romero-Pérez L, Kirchner T, de Alava E, Diaz-Martin J, Hartmann W, Baumhoer D, Antonescu CR, Szuhai K, Flucke U, Dirksen U, Pfister SM, Jones DTW, Mechtersheimer G, von Deimling A

Vol: J Cancer Res Clin Oncol. Revista Internacional
Revista Internacional

Molecular Basis of Tumor Heterogeneity in Endometrial Carcinosarcoma.

Leskela S, Pérez-Mies B, Rosa-Rosa JM, Cristobal E, Biscuola M, Palacios-Berraquero ML, Ong S, Matias-Guiu Guia X, Palacios J

Vol: Cancers (Basel). Revista Internacional
Revista Internacional

Pazopanib for treatment of advanced extraskeletal myxoid chondrosarcoma: a multicentre, single-arm, phase 2 trial.

Stacchiotti S, Ferrari S, Redondo A, Hindi N, Palmerini E, Vaz Salgado MA, Frezza AM, Casali PG, Gutierrez A, Lopez-Pousa A, Grignani G, Italiano A, LeCesne A, Dumont S, Blay JY, Penel N, Bernabeu D, de Alava E, Karanian M, Morosi C, Brich S, Dagrada GP, Vallacchi V, Castelli C, Brenca M, Racanelli D, Maestro R, Collini P, Cruz J, Martin-Broto J

Vol: Lancet Oncol. Revista Internacional
Revista Internacional

Pazopanib for treatment of advanced malignant and dedifferentiated solitary fibrous tumour: a multicentre, single-arm, phase 2 trial.

Martin-Broto J, Stacchiotti S, Lopez-Pousa A, Redondo A, Bernabeu D, de Alava E, Casali PG, Italiano A, Gutierrez A, Moura DS, Peña-Chilet M, Diaz-Martin J, Biscuola M, Taron M, Collini P, Ranchere-Vince D, Garcia Del Muro X, Grignani G, Dumont S, Martinez-Trufero J, Palmerini E, Hindi N, Sebio A, Dopazo J, Dei Tos AP, LeCesne A, Blay JY, Cruz J.

Vol: Lancet Oncol Revista Internacional
Revista Internacional

Pazopanib for treatment of advanced malignant and dedifferentiated solitary fibrous tumour: a multicentre, single-arm, phase 2 trial. (1)

Martin-Broto J, Stacchiotti S, Lopez-Pousa A, Redondo A, Bernabeu D, de Alava E, Casali PG, Italiano A, Gutierrez A, Moura DS, Peña-Chilet M, Diaz-Martin J, Biscuola M, Taron M, Collini P, Ranchere-Vince D, Garcia Del Muro X, Grignani G, Dumont S, Martinez-Trufero J, Palmerini E, Hindi N, Sebio A, Dopazo J, Dei Tos AP, LeCesne A, Blay JY, Cruz J

Vol: Lancet Oncol. Revista Internacional
Revista Internacional

Preclinical Efficacy of Endoglin-Targeting Antibody-Drug Conjugates for the Treatment of Ewing Sarcoma. (1)

Puerto-Camacho P, Amaral AT, Lamhamedi-Cherradi SE, Menegaz BA, Castillo-Ecija H, Ordóñez JL, Domínguez S, Jordan-Perez C, Diaz-Martin J, Romero-Pérez L, Lopez-Alvarez M, Civantos-Jubera G, Robles-Frías MJ, Biscuola M, Ferrer C, Mora J, Cuglievan B, Schadler K, Seifert O, Kontermann R, Pfizenmaier K, Simón L, Fabre M, Carcaboso ÁM, Ludwig JA, de Álava E

Vol: Clin Cancer Res Revista Internacional
Revista Internacional

The single nucleotide variant rs2868371 associates with the risk of mortality in non-small cell lung cancer patients: a multicenter prospective validation.

María del Valle Enguix-Riego, Jon Cacicedo Fernández de Bobadilla, Blas David Delgado León, Jose María Nieto-Guerrero Gómez, Daniel Herrero Rivera, Marco Perez, Juan Manuel Praena-Fernández, Gerardo Sanchez Carmona, Eleonor Rivin del Campo, María José Ortiz Gordillo, Jose Luis Lopez Guerra.

Vol: Radiotherapy & Oncology Revista Internacional
Revista Internacional

Tumor cell-secreted PLD increases tumor stemness by senescence-mediated communication with microenvironment.

Sandra Muñoz-Galván, Antonio Lucena-Cacace, Marco Perez, Daniel Otero-Albiol, Julian Gomez-Cambronero and Amancio Carnero.

Vol: Oncogene Revista Internacional
Revista Internacional

Tumor cell-secreted PLD increases tumor stemness by senescence-mediated communication with microenvironment. (1)

Muñoz-Galván S, Lucena-Cacace A, Perez M, Otero-Albiol D, Gomez-Cambronero J, Carnero A

Vol: Oncogene. Revista Internacional
Revista Internacional

What's in a name? Molecular subclassification of sarcomas creates fresh challenges. (1)

Díaz-Martín J, Biscuola M, Benoit J, Marcilla D, Civantos G, de Álava E

Vol: J Pathol. Revista Internacional
2018
Revista Internacional

Advanced sporadic renal epithelioid angiomyolipoma: case report of an extraordinary response to sirolimus linked to TSC2 mutation.

Espinosa M, Roldán-Romero JM, Durán I, de Álava E, Apellaniz-Ruiz M, Cascón A, Garrigós C, Robledo M, Rodríguez-Antona C.

Vol: BMC Cancer. Revista Internacional
Revista Internacional

Are EWSR1-NFATc2-positive sarcomas really Ewing sarcomas

Baldauf MC, Gerke JS, Orth MF, Dallmayer M, Baumhoer D, de Álava E, Hartmann W, Kirchner T, Grünewald TGP.

Vol: Mod Pathol. Revista Internacional
Revista Internacional

Bone sarcomas: ESMO-PaedCan-EURACAN Clinical Practice Guidelines for diagnosis, treatment and follow-up.

Casali PG, Bielack S, Abecassis N, Aro HT, Bauer S, Biagini R, Bonvalot S, Boukovinas I, Bovee JVMG, Brennan B, Brodowicz T, Broto JM, Brugières L, Buonadonna A, de Álava E, Dei Tos AP, Del Muro XG, Dileo P, Dhooge C, Eriksson M, Fagioli F, Fedenko A, Ferraresi V, Ferrari A, Ferrari S, Frezza AM, Gaspar N, Gasperoni S, Gelderblom H, Gil T, Grignani G, Gronchi A, Haas RL, Hassan B, Hecker-Nolting S, Hohenberger P, Issels R, Joensuu H, Jones RL, Judson I, Jutte P, Kaal S, Kager L, Kasper B, Kopeckova K, Krákorová DA, Ladenstein R, Le Cesne A, Lugowska I, Merimsky O, Montemurro M, Morland B, Pantaleo MA, Piana R, Picci P, Piperno-Neumann S, Pousa AL, Reichardt P, Robinson MH, Rutkowski P, Safwat AA, Schöffski P, Sleijfer S, Stacchiotti S, Strauss SJ, Sundby Hall K, Unk M, Van Coevorden F, van der Graaf WTA, Whelan J, Wardelmann E, Zaikova O, Blay JY, ESMO Guidelines Committee, PaedCan and ERN EURACAN.

Vol: Ann Oncol. Revista Internacional
Revista Internacional

Clinical association of anti-glutathione S-transferase T1 antibodies and de novo immune hepatitis after hematopoietic cell transplantation.

Aguado-Domínguez E, Sousa JM, Pérez-Simón JA, Aguilera I.

Vol: Dig Liver Dis. Revista Internacional
Revista Internacional

EphA2 receptor is a key player in the metastatic onset of Ewing sarcoma.

García-Monclús S, López-Alemany R, Almacellas-Rabaiget O, Herrero-Martín D, Huertas-Martínez J, Lagares-Tena L, Alba-Pavón P, Hontecillas-Prieto L, Mora J, de Álava E, Rello-Varona S, Giangrande PH, Tirado OM.

Vol: Int J Cancer. Revista Internacional
Revista Internacional

Ewing sarcoma.

Grünewald TGP, Cidre-Aranaz F, Surdez D, Tomazou EM, de Álava E, Kovar H, Sorensen PH, Delattre O, Dirksen U.

Vol: Nat Rev Dis Primers. Revista Internacional
Revista Internacional

Gastrointestinal stromal tumours: ESMO-EURACAN Clinical Practice Guidelines for diagnosis, treatment and follow-up.

Casali PG, Abecassis N, Bauer S, Biagini R, Bielack S, Bonvalot S, Boukovinas I, Bovee JVMG, Brodowicz T, Broto JM, Buonadonna A, de Álava E, Dei Tos AP, Del Muro XG, Dileo P, Eriksson M, Fedenko A, Ferraresi V, Ferrari A, Ferrari S, Frezza AM, Gasperoni S, Gelderblom H, Gil T, Grignani G, Gronchi A, Haas RL, Hannu A, Hassan B, Hohenberger P, Issels R, Joensuu H, Jones RL, Judson I, Jutte P, Kaal S, Kasper B, Kopeckova K, Krákorová DA, Le Cesne A, Lugowska I, Merimsky O, Montemurro M, Pantaleo MA, Piana R, Picci P, Piperno-Neumann S, Pousa AL, Reichardt P, Robinson MH, Rutkowski P, Safwat AA, Schöffski P, Sleijfer S, Stacchiotti S, Sundby Hall K, Unk M, Van Coevorden F, Van der Graaf W, Whelan J, Wardelmann E, Zaikova O, Blay JY, ESMO Guidelines Committee and EURACAN.

Vol: Ann Oncol. Revista Internacional
Revista Internacional

Identification of the cellular components involved in de novo immune hepatitis: a quantitative immunohistochemical analysis.

Aguado-Domínguez E, Gómez L, Sousa JM, Gómez-Bravo MÁ, Núñez-Roldán A, Aguilera I.

Vol: J Transl Med Revista Internacional
Revista Internacional

Lung cancer treatments efficacy in tumors with high MAP17 (PDZK1IP1) expression levels.

Irene Ferrer; Alvaro Quintanal-Villalonga, Sonia Molina-Pinelo, Jose Manuel Garcia- Heredia, Marco Perez, Rocío Suárez, Santiago Ponce-Aix, Luis Paz-Ares, Amancio Carnero.

Vol: J Exp Clin Cancer Res Revista Internacional
Revista Internacional

Preclinical Efficacy of Endoglin-Targeting Antibody-Drug Conjugates for the Treatment of Ewing Sarcoma.

Puerto-Camacho P, Amaral AT, Lamhamedi-Cherradi SE, Menegaz BA, Castillo-Ecija H, Ordóñez JL, Domínguez S, Jordan-Perez C, Diaz-Martin J, Romero-Pérez L, Lopez-Alvarez M, Civantos-Jubera G, Robles-Frías MJ, Biscuola M, Ferrer C, Mora J, Cuglievan B, Schadler K, Seifert O, Kontermann R, Pfizenmaier K, Simón L, Fabre M, Carcaboso ÁM, Ludwig JA, de Álava E.

Vol: Clin Cancer Res Revista Internacional
Revista Internacional

Proposal for the creation of a national strategy for precision medicine in cancer: a position statement of SEOM, SEAP, and SEFH.

Garrido P, Aldaz A, Vera R, Calleja MA, de Álava E, Martín M, Matías-Guiu X, Palacios J.

Vol: Clin Transl Oncol Revista Internacional
Revista Internacional

Rethinking de novo immune hepatitis, an old concept for liver allograft rejection: Relevance of glutathione S-transferase T1 mismatch.

Aguilera I, Aguado-Domínguez E, Sousa JM, Núñez-Roldán A.

Vol: World J Gastroenterol. Revista Internacional
Revista Internacional

Soft tissue and visceral sarcomas: ESMO-EURACAN Clinical Practice Guidelines for diagnosis, treatment and follow-up.

Casali PG, Abecassis N, Bauer S, Biagini R, Bielack S, Bonvalot S, Boukovinas I, Bovee JVMG, Brodowicz T, Broto JM, Buonadonna A, de Álava E, Dei Tos AP, Del Muro XG, Dileo P, Eriksson M, Fedenko A, Ferraresi V, Ferrari A, Ferrari S, Frezza AM, Gasperoni S, Gelderblom H, Gil T, Grignani G, Gronchi A, Haas RL, Hannu A, Hassan B, Hohenberger P, Issels R, Joensuu H, Jones RL, Judson I, Jutte P, Kaal S, Kasper B, Kopeckova K, Krákorová DA, Le Cesne A, Lugowska I, Merimsky O, Montemurro M, Pantaleo MA, Piana R, Picci P, Piperno-Neumann S, Pousa AL, Reichardt P, Robinson MH, Rutkowski P, Safwat AA, Schöffski P, Sleijfer S, Stacchiotti S, Sundby Hall K, Unk M, Van Coevorden F, Van der Graaf W, Whelan J, Wardelmann E, Zaikova O, Blay JY, ESMO Guidelines Committee and EURACAN.

Vol: Ann Oncol. Revista Internacional
Revista Internacional

The biological age linked to oxidative stress modifies breast cancer aggressiveness

Sáez-Freire MDM, Blanco-Gómez A, Castillo-Lluva S, Gómez-Vecino A, Galvis-Jiménez JM, Martín-Seisdedos C, Isidoro-García M, Hontecillas-Prieto L, García-Cenador MB, García-Criado FJ, Patino-Alonso MC, Galindo-Villardón P, Mao JH, Prieto C, Castellanos-Martín A, Kaderali L, Pérez-Losada J.

Vol: Free Radic Biol Med Revista Internacional
Revista Internacional

The biological age linked to oxidative stress modifies breast cancer aggressiveness (1)

Sáez-Freire MDM, Blanco-Gómez A, Castillo-Lluva S, Gómez-Vecino A, Galvis-Jiménez JM, Martín-Seisdedos C, Isidoro-García M, Hontecillas-Prieto L, García-Cenador MB, García-Criado FJ, Patino-Alonso MC, Galindo-Villardón P, Mao JH, Prieto C, Castellanos-Martín A, Kaderali L, Pérez-Losada J.

Vol: Free Radic Biol Med. Revista Internacional
Revista Internacional

The bitter side of epigenetics: variability and resistance to chemotherapy.

Hajji N, García-Domínguez DJ, Hontecillas-Prieto L, O'Neill K, de Álava E, Syed N.

Vol: Epigenomics. Revista Internacional
Revista Internacional

The combination of epigenetic drugs SAHA and HCI-2509 synergistically inhibits EWS-FLI1 and tumor growth in Ewing sarcoma.

García-Domínguez DJ, Hontecillas-Prieto L, Rodríguez-Núñez P, Pascual-Pasto G, Vila-Ubach M, García-Mejías R, Robles MJ, Tirado OM, Mora J, Carcaboso AM, de Álava E.

Vol: Oncotarget. Revista Internacional
Revista Internacional

[A child with chronic cough and weight loss].

Moreno Ortega M, Moreno García MDM, Pérez Borrego E, Gaboli M.

Vol: An Pediatr (Barc). Revista Internacional
2017
Revista Internacional

DNA methylation heterogeneity defines a disease spectrum in Ewing sarcoma.

Sheffield NC, Pierron G, Klughammer J, Datlinger P, Schönegger A, Schuster M, Hadler J, Surdez D, Guillemot D, Lapouble E, Freneaux P, Champigneulle J, Bouvier R, Walder D, Ambros IM, Hutter C, Sorz E, Amaral AT, de Álava E, Schallmoser K, Strunk D, Rinner B, Liegl-Atzwanger B, Huppertz B, Leithner A, de Pinieux G, Terrier P, Laurence V, Michon J, Ladenstein R, Holter W, Windhager R, Dirksen U, Ambros PF, Delattre O, Kovar H, Bock C, Tomazou EM.

Vol: Nat Med. Revista Internacional
Revista Internacional

DNA methylation profiling identifies PTRF/Cavin-1 as a novel tumor suppressor in Ewing sarcoma when co-expressed with caveolin-1.

Huertas-Martínez J, Court F, Rello-Varona S, Herrero-Martín D, Almacellas-Rabaiget O, Sáinz-Jaspeado M, García-Monclús S, Lagares-Tena L, Buj R, Hontecillas-Prieto L, Sastre A, Azorín D, Sanjuan X, López-Alemany R, Moran S, Roma J, Gallego S, Mora J, García Del Muro X, Giangrande PH, Peinado MA, Alonso J, de Álava E, Monk D, Esteller M, Tirado OM.

Vol: Cancer Lett. Revista Internacional
Revista Internacional

Ewing Sarcoma, an Update on Molecular Pathology with Therapeutic Implications.

de Álava E.

Vol: Surg Pathol Clin. Revista Internacional
Revista Internacional

GEIS-21: a multicentric phase II study of intensive chemotherapy including gemcitabine and docetaxel for the treatment of Ewing sarcoma of children and adults: a report from the Spanish sarcoma group (GEIS).

Mora J, Castañeda A, Pérez-Jaume S, López-Pousa A, Maradiegue E, Valverde C, Martín-Broto J, García Del Muro X, Cruz O, Cruz J, Martínez-Trufero J, Maurel J, Vaz MA, de Álava E, de Torres C.

Vol: Br J Cancer. Revista Internacional
Revista Internacional

HMGA2 overexpression predicts relapse susceptibility of blastemal Wilms tumor patients.

Hontecillas-Prieto L, García-Domínguez DJ, García-Mejías R, Ramírez-Villar GL, Sáez C, de Álava E.

Vol: Oncotarget Revista Internacional
Revista Internacional

Inflammation and stem markers association to PIM1/PIM2 kinase-induced tumors in breast and uterus.

Jiménez-García MP, Lucena-Cacace A, Robles-Frías MJ, Ferrer I, Narlik-Grassow M, Blanco-Aparicio C, Carnero A.

Vol: Oncotarget. Revista Internacional
Revista Internacional

Multidrug resistance transporter profile reveals MDR3 as a marker for stratification of blastemal Wilms tumour patients

Hontecillas-Prieto L, García-Domínguez DJ, Vaca DP, García-Mejías R, Marcilla D, Ramírez-Villar GL, Sáez C, de Álava E.

Vol: Oncotarget. Revista Internacional
Revista Internacional

The cargo protein MAP17 (PDZK1IP1) regulates the cancer stem cell pool activating the Notch pathway by abducting NUMB.

Jose Garcia-Heredia, Antonio Lucena-Cacace, Eva Verdugo-Sivianes, Marco Perez, and Amancio Carnero.

Vol: Clinical Cancer Research Revista Internacional
Revista Internacional

Tumores del estroma gastrointestinal: breve actualización y consenso de la SEAP-SEOM sobre diagnóstico patológico y molecular.

González-Cámpora R., Ramos Asensio R., Vallejo-Benítez A., Marcilla-Plaza D., Biscuola M., Martínez-Marín V., Serrano C., Hindi N., López-Guerrero J.-A., Martin-Broto J.

Vol: Rev Esp Patol Revista Internacional
2016
Revista Internacional

Dasatinib, a Src inhibitor, sensitizes liver metastatic colorectal carcinoma to oxaliplatin in tumors with high phospho-Src.

Marco Perez, Antonio Lucena-Cacace, Luis Miguel MarínGómez, Javier Padillo-Ruiz, Maria Jose Robles, Carmen Saez , Rocio Garcia Carbonero and Amancio Carnero.

Vol: Oncotarget. Revista Internacional
Revista Internacional

Efficacy of bortezomib in sarcomas with high levels of MAP17 (PDZK1IP1).

Marco Perez Javier Peinado-Serrano, Jose Manuel Garcia-Heredia, Irene Felipe Abrio, Cristina Tous, Irene Ferrer, Javier Martin-Broto, Carmen Saez, Amancio Carnero.

Vol: Oncotarget Revista Internacional
Revista Internacional

Loss of the tumor suppressor spinophilin (PPP1R9B) increases the cancer stem cell population in breast tumors.

Ferrer I, Verdugo-Sivianes EM, Castilla MA, Melendez R, Marin JJ, Muñoz-Galvan S, Lopez-Guerra JL, Vieites B, Ortiz-Gordillo MJ, De León JM, Praena- Fernandez JM, Perez M, Palacios J, Carnero A.

Vol: Oncogene Revista Internacional
2015
Revista Internacional

Efficacy of CDK4 inhibition against sarcomas depends on their levels of CDK4 mRNA and p16Ink4a.

Perez M, Muñoz-Galván S, Jiménez-García MP, Marín JJ, Carnero A.

Vol: Oncotarget Revista Internacional
Revista Internacional

MAP17 (PDZKIP1) .Expression Determines Sensitivity to the Proteasomal Inhibitor Bortezomib by Preventing Cytoprotective Autophagy and NFκB Activation in Breast Cancer.

Muñoz Galvan S, Gutierrez G, Perez M, Carnero A.

Vol: Mol Cancer Ther Revista Internacional
Revista Internacional

Unraveling heterogeneous susceptibility and the evolution of breast cancer using a systems biology approach.

Castellanos-Martín A, Castillo-Lluva S, Sáez-Freire Mdel M, Blanco-Gómez A, Hontecillas-Prieto L, Patino-Alonso C, Galindo-Villardon P, Pérez Del Villar L, Martín-Seisdedos C, Isidoro-Garcia M, Abad-Hernández MM, Cruz-Hernández JJ, Rodríguez-Sánchez CA, González-Sarmiento R, Alonso-López D, De Las Rivas J, García-Cenador B, García-Criado J, Lee DY, Bowen B, Reindl W, Northen T, Mao JH, Pérez-Losada J.

Vol: Genome Biol Revista Internacional
2014
Revista Internacional

Innovative therapies in ewing sarcoma.

Amaral AT, Ordóñez JL, Otero-Motta AP, García-Domínguez DJ, Sevillano MV, de Álava E.

Vol: Adv Anat Pathol. Revista Internacional
2013
2012
Revista Internacional

The first European interdisciplinary ewing sarcoma research summit

Kovar H, Alonso J, Aman P, Aryee DN, Ban J, Burchill SA, Burdach S, De Alava E, Delattre O, Dirksen U, Fourtouna A, Fulda S, Helman LJ, Herrero-Martin D, Hogendoorn PC, Kontny U, Lawlor ER, Lessnick SL, Llombart-Bosch A, Metzler M, Moriggl R, Niedan S, Potratz J, Redini F, Richter GH, Riedmann LT, Rossig C, Schäfer BW, Schwentner R, Scotlandi K, Sorensen PH, Staege MS, Tirode F, Toretsky J, Ventura S, Eggert A, Ladenstein R.

Vol: Front Oncol. 2012;2:54. doi: 10.3389/fonc.2012.00054. eCollection 2012. Revista Internacional
Revista Internacional

Transcription factors Sp1 and p73 control the expression of the proapoptotic protein NOXA in the response of testicular embryonal carcinoma cells to cisplatin.

Grande L, Bretones G, Rosa-Garrido M, Garrido-Martin EM, Hernandez T, Fraile S, Botella L, de Alava E, Vidal A, Garcia del Muro X, Villanueva A, Delgado MD, Fernandez-Luna JL.

Vol: J Biol Chem. 2012 Aug 3;287(32):26495-505. doi: 10.1074/jbc.M112.376319. Epub 2012 Jun 20. PubMed Revista Internacional
2011
Revista Internacional

Molecular diagnosis of dermatofibrosarcoma protuberans: a comparison between reverse transcriptase-polymerase chain reaction and fluorescence in situ hybridization methodologies.

Salgado R, Llombart B, M Pujol R, Fernández-Serra A, Sanmartín O, Toll A, Rubio L, Segura S, Barranco C, Serra-Guillén C, Yébenes M, Salido M, Traves V, Monteagudo C, Sáez E, Hernández T, de Álava E, Llombart-Bosch A, Solé F, Guillén C, Espinet B, López-Guerrero JA.

Vol: Genes Chromosomes Cancer. 2011 Jul;50(7):510-7. doi: 10.1002/gcc.20874. Epub 2011 Apr 11. Revista Internacional
Revista Internacional

Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia

Puente XS, Pinyol M, Quesada V, Conde L, Ordóñez GR, Villamor N, Escaramis G, Jares P, Beà S, González-Díaz M, Bassaganyas L, Baumann T, Juan M, López-Guerra M, Colomer D, Tubío JM, López C, Navarro A, Tornador C, Aymerich M, Rozman M, Hernández JM, Puente DA, Freije JM, Velasco G, Gutiérrez-Fernández A, Costa D, Carrió A, Guijarro S, Enjuanes A, Hernández L, Yagüe J, Nicolás P, Romeo-Casabona CM, Himmelbauer H, Castillo E, Dohm JC, de Sanjosé S, Piris MA, de Alava E, San Miguel J, Royo R, Gelpí JL, Torrents D, Orozco M, Pisano DG, Valencia A, Guigó R, Bayés M, Heath S, Gut M, Klatt P, Marshall J, Raine K, Stebbings LA, Futreal PA, Stratton MR, Campbell PJ, Gut I, López-Guillermo A, Estivill X, Montserrat E, López-Otín C, Campo E

Vol: Nature. 2011 Jun 5;475(7354):101-5. doi: 10.1038/nature10113 Revista Internacional
2010
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Cyclin D3 gene amplification in bladder

Lopez-Beltran A, Ordóñez JL, Otero AP, Blanca A, Sevillano V, Sanchez-Carbayo M, Muñoz E, Cheng L, Montironi R, de Alava E

Vol: Virchows Arch. 2010 Nov;457(5):555-61. doi: 10.1007/s00428-010-0969-6. Epub 2010 Sep 7. Revista Internacional
Revista Internacional

Imatinib plus low-dose doxorubicin in patients with advanced gastrointestinal stromal tumors refractory to high-dose imatinib: a phase I-II study by the Spanish Group for Research on Sarcomas.

Maurel J, Martins AS, Poveda A, López-Guerrero JA, Cubedo R, Casado A, Martínez-Trufero J, Ramón Ayuso J, Lopez-Pousa A, Garcia-Albeniz X, Garcia del Muro X, de Alava E

Vol: Cancer. 2010 Aug 1;116(15):3692-701. doi: 10.1002/cncr.25111. Revista Internacional
Revista Internacional

International network of cancer genome projects.

International Cancer Genome Consortium, Hudson TJ, Anderson W, Artez A, Barker AD, Bell C, Bernabé RR, Bhan MK, Calvo F, Eerola I, Gerhard DS, Guttmacher A, Guyer M, Hemsley FM, Jennings JL, Kerr D, Klatt P, Kolar P, Kusada J, Lane DP, Laplace F, Youyong L, Nettekoven G, Ozenberger B, Peterson J, Rao TS, Remacle J, Schafer AJ, Shibata T, Stratton MR, Vockley JG, Watanabe K, Yang H, Yuen MM, Knoppers BM, Bobrow M, Cambon-Thomsen A, Dressler LG, Dyke SO, Joly Y, Kato K, Kennedy KL, Nicolás P, Parker MJ, Rial-Sebbag E, Romeo-Casabona CM, Shaw KM, Wallace S, Wiesner GL, Zeps N, Lichter P, Biankin AV, Chabannon C, Chin L, Clément B, de Alava E, Degos F, Ferguson ML, Geary P, Hayes DN, Hudson TJ, Johns AL, Kasprzyk A, Nakagawa H, Penny R, Piris MA, Sarin R, Scarpa A, Shibata T, van de Vijver M, Futreal PA, Aburatani H, Bayés M, Botwell DD, Campbell PJ, Estivill X, Gerhard DS, Grimmond SM, Gut I, Hirst M, López-Otín C, Majumder P, Marra M, McPherson JD, Nakagawa H, Ning Z, Puente XS, Ruan Y, Shibata T, Stratton MR, Stunnenberg HG, Swerdlow H, Velculescu VE, Wilson RK, Xue HH, Yang L, Spellman PT, Bader GD, Boutros PC, Campbell PJ, Flicek P, Getz G, Guigó R, Guo G, Haussler D, Heath S, Hubbard TJ, Jiang T, Jones SM, Li Q, López-Bigas N, Luo R, Muthuswamy L, Ouellette BF, Pearson JV, Puente XS, Quesada V, Raphael BJ, Sander C, Shibata T, Speed TP, Stein LD, Stuart JM, Teague JW, Totoki Y, Tsunoda T, Valencia A, Wheeler DA, Wu H, Zhao S, Zhou G, Stein LD, Guigó R, Hubbard TJ, Joly Y, Jones SM, Kasprzyk A, Lathrop M, López-Bigas N, Ouellette BF, Spellman PT, Teague JW, Thomas G, Valencia A, Yoshida T, Kennedy KL, Axton M, Dyke SO, Futreal PA, Gerhard DS, Gunter C, Guyer M, Hudson TJ, McPherson JD, Miller LJ, Ozenberger B, Shaw KM, Kasprzyk A, Stein LD, Zhang J, Haider SA, Wang J, Yung CK, Cros A, Liang Y, Gnaneshan S, Guberman J, Hsu J, Bobrow M, Chalmers DR, Hasel KW, Joly Y, Kaan TS, Kennedy KL, Knoppers BM, Lowrance WW, Masui T, Nicolás P, Rial-Sebbag E, Rodriguez LL, Vergely C, Yoshida T, Grimmond SM, Biankin AV, Bowtell DD, Cloonan N, deFazio A, Eshleman JR, Etemadmoghadam D, Gardiner BB, Kench JG, Scarpa A, Sutherland RL, Tempero MA, Waddell NJ, Wilson PJ, McPherson JD, Gallinger S, Tsao MS, Shaw PA, Petersen GM, Mukhopadhyay D, Chin L, DePinho RA, Thayer S, Muthuswamy L, Shazand K, Beck T, Sam M, Timms L, Ballin V, Lu Y, Ji J, Zhang X, Chen F, Hu X, Zhou G, Yang Q, Tian G, Zhang L, Xing X, Li X, Zhu Z, Yu Y, Yu J, Yang H, Lathrop M, Tost J, Brennan P, Holcatova I, Zaridze D, Brazma A, Egevard L, Prokhortchouk E, Banks RE, Uhlén M, Cambon-Thomsen A, Viksna J, Ponten F, Skryabin K, Stratton MR, Futreal PA, Birney E, Borg A, Børresen-Dale AL, Caldas C, Foekens JA, Martin S, Reis-Filho JS, Richardson AL, Sotiriou C, Stunnenberg HG, Thoms G, van de Vijver M, van't Veer L, Calvo F, Birnbaum D, Blanche H, Boucher P, Boyault S, Chabannon C, Gut I, Masson-Jacquemier JD, Lathrop M, Pauporté I, Pivot X, Vincent-Salomon A, Tabone E, Theillet C, Thomas G, Tost J, Treilleux I, Calvo F, Bioulac-Sage P, Clément B, Decaens T, Degos F, Franco D, Gut I, Gut M, Heath S, Lathrop M, Samuel D, Thomas G, Zucman-Rossi J, Lichter P, Eils R, Brors B, Korbel JO, Korshunov A, Landgraf P, Lehrach H, Pfister S, Radlwimmer B, Reifenberger G, Taylor MD, von Kalle C, Majumder PP, Sarin R, Rao TS, Bhan MK, Scarpa A, Pederzoli P, Lawlor RA, Delledonne M, Bardelli A, Biankin AV, Grimmond SM, Gress T, Klimstra D, Zamboni G, Shibata T, Nakamura Y, Nakagawa H, Kusada J, Tsunoda T, Miyano S, Aburatani H, Kato K, Fujimoto A, Yoshida T, Campo E, López-Otín C, Estivill X, Guigó R, de Sanjosé S, Piris MA, Montserrat E, González-Díaz M, Puente XS, Jares P, Valencia A, Himmelbauer H, Quesada V, Bea S, Stratton MR, Futreal PA, Campbell PJ, Vincent-Salomon A, Richardson AL, Reis-Filho JS, van de Vijver M, Thomas G, Masson-Jacquemier JD, Aparicio S, Borg A, Børresen-Dale AL, Caldas C, Foekens JA, Stunnenberg HG, van't Veer L, Easton DF, Spellman PT, Martin S, Barker AD, Chin L, Collins FS, Compton CC, Ferguson ML, Gerhard DS, Getz G, Gunter C, Guttmacher A, Guyer M, Hayes DN, Lander ES, Ozenberger B, Penny R, Peterson J, Sander C, Shaw KM, Speed TP, Spellman PT, Vockley JG, Wheeler DA, Wilson RK, Hudson TJ, Chin L, Knoppers BM, Lander ES, Lichter P, Stein LD, Stratton MR, Anderson W, Barker AD, Bell C, Bobrow M, Burke W, Collins FS, Compton CC, DePinho RA, Easton DF, Futreal PA, Gerhard DS, Green AR, Guyer M, Hamilton SR, Hubbard TJ, Kallioniemi OP, Kennedy KL, Ley TJ, Liu ET, Lu Y, Majumder P, Marra M, Ozenberger B, Peterson J, Schafer AJ, Spellman PT, Stunnenberg HG, Wainwright BJ, Wilson RK, Yang H.

Vol: Nature. 2010 Apr 15;464(7291):993-8. doi: 10.1038/nature08987. Revista Internacional
Revista Internacional

Molecular predictors of efficacy of adjuvant weekly paclitaxel in early breast cancer

Martín M, Rodríguez-Lescure A, Ruiz A, Alba E, Calvo L, Ruiz-Borrego M, Santaballa A, Rodríguez CA, Crespo C, Abad M, Domínguez S, Florián J, Llorca C, Méndez M, Godes M, Cubedo R, Murias A, Batista N, García MJ, Caballero R, de Alava E

Vol: Breast Cancer Res Treat. 2010 Aug;123(1):149-57. doi: 10.1007/s10549-009-0663-z. Revista Internacional
2009
Revista Internacional

In vitro and in vivo rationale for the triple combination of panobinostat (LBH589) and dexamethasone with either bortezomib or lenalidomide in multiple myeloma

Ocio EM, Vilanova D, Atadja P, Maiso P, Crusoe E, Fernández-Lázaro D, Garayoa M, San-Segundo L, Hernández-Iglesias T, de Alava E, Shao W, Yao YM, Pandiella A, San-Miguel JF.

Vol: Haematologica. 2010 May;95(5):794-803. doi: 10.3324/haematol.2009.015495. Epub 2009 Nov 30 Revista Internacional
Revista Internacional

Other targetable sarcomas

Pires de Camargo V, van de Rijn M, Maestro R, de Alava E, Madoz-Gúrpide J, Pilotti S, von Mehren M, Pedeutour F, Maki RG, Rutkowski P, Thomas DM

Vol: Semin Oncol. 2009 Aug;36(4):358-71. doi: 10.1053/j.seminoncol.2009.06.008. Revista Internacional
Revista Internacional

Stable interference of EWS-FLI1 in an Ewing sarcoma cell line impairs IGF-1/IGF-1R signalling and reveals TOPK as a new target

Herrero-Martín D, Osuna D, Ordóñez JL, Sevillano V, Martins AS, Mackintosh C, Campos M, Madoz-Gúrpide J, Otero-Motta AP, Caballero G, Amaral AT, Wai DH, Braun Y, Eisenacher M, Schaefer KL, Poremba C, de Alava E.

Vol: Br J Cancer. 2009 Jul 7;101(1):80-90. doi: 10.1038/sj.bjc.6605104. Epub 2009 Jun 2. Revista Internacional
Revista Internacional

Zalypsis: a novel marine-derived compound with potent antimyeloma activity that reveals high sensitivity of malignant plasma cells to DNA double-strand breaks.

Ocio EM, Maiso P, Chen X, Garayoa M, Alvarez-Fernández S, San-Segundo L, Vilanova D, López-Corral L, Montero JC, Hernández-Iglesias T, de Alava E, Galmarini C, Avilés P, Cuevas C, San-Miguel JF, Pandiella A.

Vol: Blood. 2009 Apr 16;113(16):3781-91. doi: 10.1182/blood-2008-09-177774. Epub 2008 Nov 19. Revista Internacional
2008