Cardiovascular and Respiratory Pathology/Other Systemic Diseases

Group for the Study of Disability and Rehabilitation


Cód. SSPA: IBiS-DS-11

The research activity of our group focuses on processes with a high impact on disability in today's society. It focuses mainly on highly prevalent processes such as stroke or cardiovascular disease, as well as processes with lower incidence that produce severe disability such as traumatic spinal cord injury, Traumatic Brain Injury.

Lines of research

  • Rehabilitation of patients with acquired brain injury (ABI), with three fundamental lines:

-Study and Treatment of Acquired Brain Injury due to Traumatic Brain Injury

-Comprehensive Rehabilitation in Stroke Patients

-Diagnosis and treatment of neurocognitive deficit in ABD

  • Comprehensive rehabilitation in patients with traumatic spinal cord injury.
  • Cardiac Rehabilitation and Secondary Prevention.
  • Children's Rehabilitation.
  • Diagnosis and instrumental evaluation of movement disorders.
  • Study and treatment of musculoskeletal pathology and interventionism.


Within these lines of research, competitive clinical trials are currently underway, which are as follows:

  • Phase IIA, randomized, double-blind, placebo-controlled, parallel-group, multicenter clinical trial to evaluate the safety, tolerability, and therapeutic efficacy of daily oral treatment with NFX88 on neuropathic pain in patients with spinal cord injury.
  • Preliminary, randomized, double-blind, placebo-controlled demonstrative study to evaluate the safety and efficacy of elezanumab in subjects with acute traumatic cervical spinal cord injury.

Research projects

Impact of a protocolized physiotherapy action in home care on patients with stroke sequelae: effect on the patient and caregiver.

Development of biomechanical models for kinetic and electromyographic assessment for application in the treatment of patients with cerebrovascular disease. BIACTIVA: R+D+i projects» universities and public research entities (BOJA no. 239, of December 15, 2021)

Determination of the anatomical changes of the median nerve and their relationship with symptomatic and functional improvement in moderate-severe carpal tunnel syndrome after surgical treatment.


  • Clinical Trials:

Advances in pharmacological treatment in Muscular Dystrophy: With our incorporation into multicenter clinical trials currently under development at European level.

Clinical Study to Evaluate the Efficacy and Safety of Givinostat in Ambulant Patients with Duchenne Muscular Dystrophy. NCT02851797

Advances in the pharmacological treatment of Spinal Muscular Atrophy: Incorporation into multicenter clinical trials under development at European level.

A Study to Investigate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Efficacy of Risdiplam (RO7034067) in Type 2 and 3 Spinal Muscular Atrophy (SMA) Participants. NCT02908685


  • Research Projects:

Design and development of prosthetic sockets: Socket Sense. EU-funded research project currently under development.

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